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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">IPROC</journal-id>
      <journal-id journal-id-type="nlm-ta">iproc</journal-id>
      <journal-title>Iproceedings</journal-title>
      <issn pub-type="epub">2369-6893</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
    <article-id pub-id-type="publisher-id">v4i1e10579</article-id>
    <article-id pub-id-type="pmid"/>
    <article-id pub-id-type="doi">10.2196/10579</article-id>
    <article-categories>
      <subj-group subj-group-type="heading">
        <subject>Abstract</subject>
      </subj-group>
      <subj-group subj-group-type="article-type">
        <subject>Abstract</subject>
      </subj-group>
    </article-categories>
    <title-group>
      <article-title>Investigation of Cholera Outbreak at Rawalpindi, Pakistan - August 2017</article-title>
    </title-group>
    <contrib-group>
      <contrib contrib-type="editor">
        <name>
          <surname>Khader</surname>
          <given-names>Yousef</given-names>
        </name>
      </contrib>
    </contrib-group>
    <contrib-group>
      <contrib contrib-type="author" id="contrib1" corresp="yes">
        <name name-style="western">
          <surname>Akram</surname>
          <given-names>Khurram</given-names>
        </name>
      </contrib>
    </contrib-group>
    <author-notes>
      <corresp>Corresponding Author: Khurram Akram 
      <email>drkhurram114@gmail.com</email></corresp>
    </author-notes>
    <pub-date pub-type="collection"><season>Jan-Dec</season><year>2018</year></pub-date>
    <pub-date pub-type="epub">
      <day>29</day>
      <month>03</month>
      <year>2018</year>
    </pub-date>
    <volume>4</volume>
    <issue>1</issue>
    <elocation-id>e10579</elocation-id>
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    <history>
      <date date-type="received">
        <day>29</day>
        <month>3</month>
        <year>2018</year>
      </date>
      <date date-type="accepted">
        <day>29</day>
        <month>3</month>
        <year>2018</year>
      </date>
    </history>
    <!--(c) the authors - correct author names and publication date here if necessary. Date in form ', dd.mm.yyyy' after jmir.org-->
    <copyright-statement>©Khurram Akram. Originally published in Iproceedings (http://www.iproc.org), 29.03.2018.</copyright-statement>
    <copyright-year>2018</copyright-year>
    <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
      <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in Iproceedings, is properly cited. The complete bibliographic information, a link to the original publication on http://www.iproc.org/, as well as this copyright and license information must be included.</p>
    </license>  
    <self-uri xlink:href="http://www.iproc.org/2018/1/e10579/" xlink:type="simple"/>
    <abstract>
      <sec sec-type="background">
        <title>Background</title>
        <p>Cholera is endemic in Pakistan with many outbreaks during the summer season. On July 29, 2017, two suspected cholera cases were reported from a tertiary care hospital in Rawalpindi. On the request of District Health Authorities, a team was constituted.</p>
      </sec>
      <sec sec-type="objective">
        <title>Objective</title>
        <p>To assess the magnitude of the outbreak, evaluate possible risk factors and recommend control measures.</p>
      </sec>
      <sec sec-type="methods">
        <title>Methods</title>
        <p>Investigation was carried out from Aug 01-15, 2017. Hospital records were reviewed, and active case-finding was conducted. A case was defined as sudden onset of loose watery stools (3 in past 24 hours) with any of the symptoms like vomiting, nausea, abdominal cramps or fever in a resident of Dhok-Paracha, Amarpura &#38; Dhok-Chaudhriyan, Rawalpindi, from July 19-August 07, 2017. Age and sex-matched neighborhood controls were enrolled. Data was collected using a structured questionnaire. Four stool samples and three water samples were sent to National Institute of Health for microbiological analysis</p>
      </sec>
      <sec sec-type="results">
        <title>Results</title>
        <p>A total of 30 cases with 02 deaths (CFR 2.2%) were identified out of which 28 cases were detected through active case-search. There was a male predominance (n=20, 66%) with mean age of 13.7 years (range: 02 months-55 years). Overall AR was 0.68% with 16-20 years being the most severely affected age group (AR 1.8%). Out of 30 cases, 14 were consuming well-water (OR 10.37, 95% CI 3.61-29.74) and 12 were consuming tap water (OR 3.94, 95% CI 1.54-10.08). Water samples showed presence of coliforms (240 CFU/100 ml). Vibrio Cholera Serotype Inaba isolated from stool samples. Heavy rainfall was recorded (455.5 ml) from June 26 to August 6, 2017.</p>
      </sec>
      <sec sec-type="conclusions">
        <title>Conclusions</title>
        <p>Consumption of contaminated water was the most probable cause of the outbreak. Contamination of water sources during recent flash floods was the source of contamination. Chlorination of water sources was conducted. Health awareness sessions on safe drinking water were conducted in the community.</p>
      </sec>
    </abstract></article-meta>
  </front>
</article>
