<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "http://dtd.nlm.nih.gov/publishing/2.0/journalpublishing.dtd">
<article article-type="abstract" dtd-version="2.0" xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">IPROC</journal-id>
      <journal-id journal-id-type="nlm-ta">iproc</journal-id>
      <journal-title>Iproceedings</journal-title>
      <issn pub-type="epub">2369-6893</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v7i1e35429</article-id>
      <article-id pub-id-type="pmid">27762275</article-id>
      <article-id pub-id-type="doi">10.2196/35429</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Abstract</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Abstract</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Crusted Scabies as a Suitable Disease for Teledermatology: A Study of 2 Cases</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Derrick</surname>
            <given-names>Thomas</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Bimbi</surname>
            <given-names>César</given-names>
          </name>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of Dermatology</institution>
            <institution>Dermatologia Medica &amp; Laser Clinic</institution>
            <addr-line>R. 24 de Outubro, 111 - Sala 502 - Independência</addr-line>
            <addr-line>Porto Alegre, 90510-002</addr-line>
            <country>Brazil</country>
            <phone>55 51 3228 8124</phone>
            <email>cbimbi@terra.com.br</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-6396-7767</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Dalla Lana</surname>
            <given-names>Daiane Flores</given-names>
          </name>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3612-7305</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Brzezinski</surname>
            <given-names>Piotr</given-names>
          </name>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-6817-606X</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Kyriakou</surname>
            <given-names>Georgia</given-names>
          </name>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-3907-5654</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Dermatology</institution>
        <institution>Dermatologia Medica &amp; Laser Clinic</institution>
        <addr-line>Porto Alegre</addr-line>
        <country>Brazil</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Post-Graduate Program in Pathology</institution>
        <institution>Federal University of Health Sciences of Porto Alegre (UFCSPA)</institution>
        <addr-line>Porto Alegre</addr-line>
        <country>Brazil</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Department of Physiotherapy and Medical Emergency</institution>
        <institution>Faculty of Health Sciences</institution>
        <institution>Pomeranian Academy</institution>
        <addr-line>Slupsk</addr-line>
        <country>Poland</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Department of Dermatology</institution>
        <institution>University General Hospital of Patras</institution>
        <addr-line>Rion</addr-line>
        <country>Greece</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: César Bimbi <email>cbimbi@terra.com.br</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <season>Jan-Dec</season>
        <year>2021</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>10</day>
        <month>12</month>
        <year>2021</year>
      </pub-date>
      <volume>7</volume>
      <issue>1</issue>
      <elocation-id>e35429</elocation-id>
      <history>
        <date date-type="received">
          <day>3</day>
          <month>12</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>3</day>
          <month>12</month>
          <year>2021</year>
        </date>
      </history>
      <copyright-statement>©César Bimbi, Daiane Flores Dalla Lana, Piotr Brzezinski, Georgia Kyriakou. Originally published in Iproceedings (https://www.iproc.org), 10.12.2021.</copyright-statement>
      <copyright-year>2021</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in Iproceedings, is properly cited. The complete bibliographic information, a link to the original publication on https://www.iproc.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.iproc.org/2021/1/e35429" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Teledermatology has been available for several years now, but the COVID-19 pandemic has highlighted its importance, especially in remote communities. Crusted scabies (CS) presents a unique clinical picture that favors telediagnosis. Patients with neurological diseases, as well as homeless, HIV-infected patients and people with impaired immunological function, are at risk. Clusters of CS have been reported in French Guyana, and these were associated with human T-lymphotropic virus infections. CS has also been reported in Aboriginal Australian communities.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>Teledermatology is especially useful in cases of CS, as it is a disease that affects areas that are in need of medical services. At the same time, CS presents a unique clinical picture. The objective of this presentation is to fuel the clinical suspicion and detection of patients with this debilitating condition.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>Relatives of patient 1 contacted our clinic for teledermatology appointments. General practitioners from health services sent images of the second patient.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>Case 1 involved an older woman living in a nursing home with Alzheimer disease, which was severe enough to constrain her to bed. We recommended that her relatives (who had sent images) collect skin scrapings in a container. These scrapings were sent to a clinical analysis laboratory where microscopic potassium hydroxide preparation revealed the presence of <italic>Sarcoptes</italic> mites. Treatment with oral ivermectin and topical permethrin resulted in the complete resolution of the lesions. Case 2 involved a homeless, HIV-positive, 42-year-old male. The images were sent by clinicians from local health services. This patient was also treated with oral ivermectin and permethrin lotion. We recognize that this case would need further diagnostic workup, but it is highly indicative of CS.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>CS is one of the most suited diseases for the practice of teledermatology for widespread, large, hyperkeratotic fissured plaques covered with abundant, silvery scales for which the expression “once seen, never forgotten” is highly applicable. These cases are gratifyingly simple to treat, and patients benefit from rapid clinical improvement. Prompt diagnoses prevent outbreaks of scabies for relatives and medical personnel, since these skin crusts contain large numbers of scabies mites. CS has been increasingly reported but poorly recognized, and it has often been misdiagnosed as psoriasis. Images, such as those shown in this presentation, are unique and are enough to raise strong clinical suspicion.</p>
        </sec>
        <sec>
          <title>Conflicts of Interest</title>
          <p>None declared.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>crusted scabies</kwd>
        <kwd>teledermatology</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>1a and 1b: White-silvery scales over the hands and arms; 1c: Mites and its black round fecal matter (scybala)  through microscopic examination; 1d: Significant clinical improvement after treatment.</p>
        <media xlink:href="iproc_v7i1e35429_app1.png" xlink:title="PNG File , 2440 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>2a: Disseminated hyperkeratotic lesions covered with thick, silvery-white scales over the legs and feet; 2b: Extensive erythema and crusted edema over arms.</p>
        <media xlink:href="iproc_v7i1e35429_app2.png" xlink:title="PNG File , 1112 KB"/>
      </supplementary-material>
    </app-group>
  </back>
</article>
