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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">IPROC</journal-id>
      <journal-id journal-id-type="nlm-ta">iproc</journal-id>
      <journal-title>Iproceedings</journal-title>
      <issn pub-type="epub">2369-6893</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v8i1e36361</article-id>
      <article-id pub-id-type="pmid"/>
      <article-id pub-id-type="doi">10.2196/36361</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Abstract</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Abstract</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Foodborne Outbreak Investigation in Al-Ahsa, Saudi Arabia, 2021: A Retrospective Cohort Study</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Khader</surname>
            <given-names>Yousef</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes" equal-contrib="yes">
          <name name-style="western">
            <surname>Alahmad</surname>
            <given-names>Abdulmohsen</given-names>
          </name>
          <degrees>BDS</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Saudi Field Epidemiology Training Program</institution>
            <addr-line>Riyadh, 12282</addr-line>
            <country>Saudi Arabia</country>
            <phone>966 0503300449</phone>
            <email>abdulmohsen.moh@gmail.com</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8925-0679</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Kamel</surname>
            <given-names>Shady Abdulrahman</given-names>
          </name>
          <xref rid="aff1" ref-type="aff">1</xref>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Saudi Field Epidemiology Training Program</institution>
        <addr-line>Riyadh</addr-line>
        <country>Saudi Arabia</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Abdulmohsen Alahmad <email>abdulmohsen.moh@gmail.com</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <season>Jan-Dec</season>
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>3</day>
        <month>2</month>
        <year>2022</year>
      </pub-date>
      <volume>8</volume>
      <issue>1</issue>
      <elocation-id>e36361</elocation-id>
      <history>
        <date date-type="received">
          <day>12</day>
          <month>1</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>17</day>
          <month>1</month>
          <year>2022</year>
        </date>
      </history>
      <copyright-statement>©Abdulmohsen Alahmad, Shady Abdulrahman Kamel. Originally published in Iproceedings (https://www.iproc.org), 03.02.2022.</copyright-statement>
      <copyright-year>2022</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in Iproceedings, is properly cited. The complete bibliographic information, a link to the original publication on https://www.iproc.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.iproc.org/2022/1/e36361" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>On September 10, 2021, Al-Ahsa General Health Directorate reported an unexpected number of patients had presented with gastrointestinal symptoms. All the patients gave a history of sharing a common meal as they ate dinner that was served at the mother’s house in a family gathering on September 9, 2021, at 9 PM in Al-Ahsa.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study aims to confirm the existence of the outbreak, confirm the diagnosis, define and identify the cases, identify the source of the outbreak, determine the causative agent or organism if possible and its mode of transmission, and recommend preventive measures to be applied to prevent similar outbreaks in the future.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>A retrospective cohort design was used in this outbreak investigation to identify its source. Cases were defined as any person who ate dinner at the family gathering on September 9, 2021, and developed any or a combination of the following symptoms: diarrhea, vomiting, fever, or abdominal pain within 26 hours of food consumption. We collected information on demographics, symptoms, and food history using a semistructured questionnaire. We reviewed hospital records for symptoms and vital signs. We reviewed available laboratory results for cases, and we conducted an active case search to identify more cases. The data obtained was analyzed using SPSS version 21.0 (IBM Corp).</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>A total of 20 (74%) were defined as cases and 7 (26%) as noncases. Of 20 cases, 16 (80%) were females and 4 (20%) were males. The ages ranged between 2-70 years. Among cases, 59.3% had vomiting, 59.3% had a fever, 48.1% developed diarrhea, and 25% had abdominal pain. The incubation period ranged from 10 to 26 hours, with a mean of 17.8 hours. The risk ratios (relative risks) and <italic>P</italic> values were calculated for each food item to assess the association between consumption of individual food items and subsequent illness. Among 8 food items consumed, red pasta with chicken (relative risk 37.3, 95% CI 3.2-424.6) and beef pizza (relative risk 6.5, 95% CI 1.74-42.2) were significantly associated with illness.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>According to the epidemiological investigation, symptoms, incubation period, and laboratory results, there might be some differential diagnosis, but we were unable to more definitively identify the source of the outbreak. We recommend more education to the households about food safety.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>foodborne</kwd>
        <kwd>cohort</kwd>
        <kwd>outbreak</kwd>
        <kwd>gastroenteritis</kwd>
        <kwd>Saudi Arabia</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body/>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Foodborne Outbreak Investigation in Al-Ahsa, Saudi Arabia, 2021: A Retrospective Cohort Study.</p>
        <media xlink:href="iproc_v8i1e36361_app1.pdf" xlink:title="PDF File  (Adobe PDF File), 553 KB"/>
      </supplementary-material>
    </app-group>
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