Dengue fever (DF) has re-emerged in Yemen with a higher frequency during the last years. On November 6, 2019, an increased number of suspected DF cases in Al-Garrahi district was reported. On November 7, 2019, a team was sent to investigate.

This study aims to confirm the existence of an outbreak, describe the outbreak characteristics, and recommend suitable intervention for control.

A descriptive study was conducted. The World Health Organization case definition was used to identify patients. An active search from house to house, along with entomological investigation and health education, was conducted. A line list was used to collect data. Blood specimens were collected and tested by enzyme-linked immunosorbent assay for dengue IgM. Frequency, percentage, and rates were calculated, and the population from the central statistical organization was used.

A total of 2067 cases met the case definition. Of them, 51% were males and 32% were aged <10 years. All patients complained of fever, headache, and arthralgia (100%), followed by myalgia and retro-orbital pain (67% and 39%, respectively). The first case patient was in week 41, and the peak was reached with 1058 patients in week 46. The overall attack rate was 16 of 1000, significantly higher among patients aged 10 years to <50 years and ≥50 years compared with patients aged <10 years (17 and 19/1000 vs 14/1000; P<.001). Of 20 tested blood samples, 12 (60%) were IgM positive. The house index was 70%, the container index was 50%, and the Breteau index was 140. Vector control measures with community participation were intensified in week 46, and patient cases decreased to 140 in week 48.

A dengue outbreak was confirmed in Al-Garrahi district. The spread of infection was facilitated by storing water and the presence of indoor larvae. The findings emphasize the importance of health awareness and community participation for containing DF outbreaks.