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<article article-type="abstract" dtd-version="2.0" xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">IPROC</journal-id>
      <journal-id journal-id-type="nlm-ta">iproc</journal-id>
      <journal-title>Iproceedings</journal-title>
      <issn pub-type="epub">2369-6893</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v8i1e36511</article-id>
      <article-id pub-id-type="pmid"/>
      <article-id pub-id-type="doi">10.2196/36511</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Abstract</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Abstract</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Pattern of Comorbidities and the Impact on Outcomes in Patients With COVID-19 in Babel Governorate, Iraq, in 2020</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Khader</surname>
            <given-names>Yousef</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Hussein</surname>
            <given-names>Alaa</given-names>
          </name>
          <degrees>MBChB</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Ministry of Higher Education and Scientific Research</institution>
            <addr-line>Babil Health Directorate, Public Health Department</addr-line>
            <addr-line>Al Mussaib Health District</addr-line>
            <addr-line>Babil Al-Hilla</addr-line>
            <country>Iraq</country>
            <phone>964 07801531937</phone>
            <email>Alaa.hussein1300a@comed.uobaghdad.edu.iq</email>
          </address>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Lami</surname>
            <given-names>Faris</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-3673-3818</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Ministry of Higher Education and Scientific Research</institution>
        <addr-line>Babil Al-Hilla</addr-line>
        <country>Iraq</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Alaa Hussein <email>Alaa.hussein1300a@comed.uobaghdad.edu.iq</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <season>Jan-Dec</season>
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>24</day>
        <month>2</month>
        <year>2022</year>
      </pub-date>
      <volume>8</volume>
      <issue>1</issue>
      <elocation-id>e36511</elocation-id>
      <history>
        <date date-type="received">
          <day>16</day>
          <month>1</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>24</day>
          <month>1</month>
          <year>2022</year>
        </date>
      </history>
      <copyright-statement>©Alaa Hussein, Faris Lami. Originally published in Iproceedings (https://www.iproc.org), 24.02.2022.</copyright-statement>
      <copyright-year>2022</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in Iproceedings, is properly cited. The complete bibliographic information, a link to the original publication on https://www.iproc.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.iproc.org/2022/1/e36511" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Comorbidities pose a major clinical challenge to the care and treatment of patients with COVID-19.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study aimed to evaluate the effects of common comorbidities on the severity, outcome, and length of stay in the hospital for patients with COVID-19 in Babel Governorate, Iraq, in 2020.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>All laboratory-confirmed cases of COVID-19 in the 2 COVID-19 hospitals in Babel Governorate from March through September 2020 were included. We developed a form to document sociodemographic data, clinical presentation, severity, comorbidities, length of hospital stay, and outcomes.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p> A total of 2574 patients were included; 1581 (61.4%) were men. The mean age was 48.7 (SD 16.4) years. There were 1212 (47.1%) severe cases and 489 (19%) critical cases. There were 1543 (59.9%) patients with no comorbidity, 536 (20.9%) patients with 1 comorbidity, and 495 (19.2%) patients with 2 or more comorbidities. The most common comorbidity was diabetes mellitus (643/1599, 25%), followed by hypertension (598/1599, 23.4%). The proportion of severe or critical cases among the patients with comorbidities was 84% (865/1031) compared to 54.1% (836/1543) among the patients with no comorbidity (<italic>P</italic>&lt;.001). About 12% (125/1031) of patients with comorbidities had a mean hospitalization time &gt;2 weeks compared to the 8% (123/1543) of patients with no comorbidity (<italic>P</italic>&lt;.001). The case-fatality ratio was 26.4% (272/1031) in patients with comorbidities compared to 10.6% (163/1543) in patients with no comorbidity (<italic>P</italic>&lt;.001).</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>Comorbidity is a significant predictor of serious hospital course and fatal outcomes in patients with COVID-19. Patients with comorbidities must be vigilant with preventive measures and should be prioritized for COVID-19 vaccination.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>comorbidities</kwd>
        <kwd>COVID-19</kwd>
        <kwd>Iraq</kwd>
        <kwd>hypertension</kwd>
        <kwd>diabetes</kwd>
        <kwd>2020</kwd>
      </kwd-group>
    </article-meta>
  </front>
</article>
